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Benchmarks › Hydration, Therapeutic, Prophylactic, Diagnostic Injections and Infusions and Chemotherapy and Other Highly Complex Biologic Agent Administration

Hydration, Therapeutic, Prophylactic, Diagnostic Injections and Infusions and Chemotherapy and Other Highly Complex Biologic Agent Administration: Federal IDR benchmarks

In 2025-Q4 the median prevailing offer for Hydration, Therapeutic, Prophylactic, Diagnostic Injections and Infusions and Chemotherapy and Other Highly Complex Biologic Agent Administration (CPT 96360 - 96549) was 424% of the QPA, across 20,079 payment determinations covering 42,499 items or services.

QuarterMedian prevailing offer, % of QPADeterminationsItems or services
2025-Q1368%8,03515,917
2025-Q2400%14,10128,729
2025-Q3428%24,31353,843
2025-Q4424%20,07942,499

Source: CMS Federal IDR Supplemental Tables, reporting year 2025 (CMS reports page). Quarterly medians cannot be combined into a yearly median, so each quarter is shown separately.

What this does and does not tell you

A median describes the middle of past outcomes for the whole specialty. It is not a prediction for a specific claim: the QPA band, the plan, the state, the evidence you submit and the entity all matter. Lower-QPA items tend to see higher multiples; see QPA bands.

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